Detection and Identification of Illicit and Hazardous Substances with Proton-Transfer-Reaction Mass Spectrometry (PTR-MS)
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چکیده
The innovative Proton-Transfer-Reaction Mass Spectrometry (PTR-MS) technology was invented and developed in the 1990s by scientists at the "Institut für Ionenphysik" at the Leopold-Franzens Universität in Innsbruck and was commercialized by the spin-off company IONICON Analytik GmbH. PTR-MS rapidly became a well established analytical technology in the fields of environmental research, atmospheric chemistry, and food and flavor science [1]. This resulted from its high selectivity (up to 8 000 m/Δm), extremely low detection limits (sub-pptv levels), rapid response times (100 ms) and real-time quantification capability. Here we present our latest studies on using PTR-MS in the analysis of explosives (TNT, RDX, PETN, Semtex, etc.) in the gas and in the liquid phase, as well as chemical warfare agents (CWAs) and illicit, prescribed and designer drugs [2-4]. It turns out that PTR-MS can detect all of these substances even in smallest concentrations with high selectivity. Therefore, even in a complex chemical environment we are able to detect threat agents with high levels of confidence, thus nearly eliminating so-called "false positives". Moreover, from the beginning of 2008 until 2011, Ionicon was a partner in the European Defence Agency (EDA) JIP-FP project "GUARDED". In this three-year project, we developed a rugged and compact PTR-MS instrument for use on a robot platform. Details about the outcome of this project will
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